Highlights

  • ITP signaling and homeostasis

    The ion transport peptide (ITP) signaling system relies on a guanylate cyclase receptor to maintain homeostasis in Drosophila.

    Jayati Gera, Marishia Agard ... Meet Zandawala
    Research Article

  • Modelling archaeal membranes

    Archaea use single-headed and double-headed lipids to construct cell membranes that are both flexible and capable of withstanding extreme environments.

    Miguel Amaral, Felix Frey ... Anđela Šarić
    Research Article

  • Focus Issue: Trained Immunity

    The articles in this focus issue discuss progress towards a better understanding of memory in the innate immune system, and efforts to develop new vaccines and therapeutics based on “trained immunity”.

    Collection

  • How we understand each other

    eLife author Joe Barnby answers questions about a study that explored how humans navigate social interactions.

    Inside eLife

  • No change for astroctyes

    Genetically removing the RNA-binding protein PTBP1 from astrocytes does not convert them into neurons, contrary to previous claims.

    Min Zhang, Naoto Kubota ... Sika Zheng
    Research Article

  • Drug-resistant sleeping sickness

    Mutations in a water channel called TbAQP2 make the parasite that causes sleeping sickness resistant to drugs. Image: Jessica Eggers (CC BY 4.0).

    Modestas Matusevicius, Robin A Corey ... Simone N Weyand
    Reviewed Preprint Updated
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Neuroscience

    Executive Resources Shape the Impact of Language Predictability Across the Adult Lifespan

    Merle Schuckart, Sandra Martin ... Jonas Obleser
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Structural basis for collagen recognition by the Streptococcus pyogenes M3 protein and its involvement in biofilm

    Marta Wojnowska, Takeaki Wajima ... Ulrich Schwarz-Linek
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Genetics and Genomics

    Functional analysis across model systems implicates ribosomal proteins in growth and proliferation defects associated with hypoplastic left heart syndrome

    Tanja Nielsen, Anaïs Kervadec ... Alexandre R Colas
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cancer Biology

    Endoscopic liquid biopsies of gastric fluid in a large patient cohort reveal DNA content as a candidate tumor biomarker in gastric cancer

    Francine Carla Cadoná, Thais F Bartelli ... Emmanuel Dias-Neto
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Glycosylated IgG antibodies contribute to the recovery of haemorrhagic fever with renal syndrome patients

    Chuansong Quan, Lu Wang ... Haifeng Hou
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology

    Phenylhydrazone-based Endoplasmic Reticulum Proteostasis Regulator Compounds with Enhanced Biological Activity

    Gabriel M Kline, Lisa Boinon ... R Luke Wiseman
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology

    E(spl)m4 Directly Antagonizes Traf4 to Inhibit JNK Signaling in Drosophila

    Katrin Strobel, Jennifer Falconi ... Alexandre Djiane
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Medicine

    Are peer reviewers influenced by their work being cited?

    Adrian Barnett
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease
    2. Ecology

    Dark matter of an orchid: metagenome of the microbiome associated with the rhizosphere of Dactylorhiza traunsteineri

    Gabriel A Vignolle, Leopold Zehetner ... Julien Charest
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Fish CDK2 recruits Dtx4 to degrade TBK1 through ubiquitination in the antiviral response

    Long-Feng Lu, Can Zhang ... Shun Li
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
Load more

Magazine

  1. Research Culture: The SAFE Labs Handbook as a tool for improving lab culture

    Erika Donà, James M Gahan ... Philip Coen
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Metabolism: How one nutrient controls cell size

    Angela Montero, Lydia WS Finley
    1. Genetics and Genomics

    Transgenerational Epigenetic Inheritance: Twists and turns in the story of learned avoidance

    Lesley T MacNeil
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease
    3. Medicine

    Focus Issue: Trained Immunity

    Edited by Satyajit Rath et al.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Focus Issue: Evolving our understanding of trained immunity

    Eva Kaufmann, Yahya Sohrabi ... Jos WM van der Meer
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Bacteriology: How Shigella tackles host defences

    Yizhou Huang, Teresa LM Thurston
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Chromosomes: Exploring a crossroads in the aging process

    Kiyan Shabestary, Daniel E Gottschling
  8. See more Magazine articles

Categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Plant Biology
  17. Stem Cells and Regenerative Medicine
  18. Structural Biology and Molecular Biophysics
Back to top