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Highlights

  • Complex connections

    Optogenetics reveals that interactions between the basal ganglia and the pedunculopontine nucleus (PPN), a region that has a central role in motor control, are more complex than previously thought.

    Michel Fallah, Kenea C Udobi ... Rebekah C Evans
    Research Article

  • The benefits of disorder

    The presence of an intrinsically disordered region in a transcription factor enhances both target binding and search efficiency.

    Wencheng Ji, Ori Hachmo ... Ariel Amir
    Reviewed Preprint Updated

  • Genetic parallels

    Multiple genetic analyses reveal surprising parallels between biomineralization in stony corals and certain sponges.

    Oliver Voigt, Magdalena V Wilde ... Gert Wörheide
    Research Article

Latest research

    1. Cell Biology

    Human receptive endometrial assembloid for deciphering the implantation window

    Yu Zhang, Rusong Zhao ... Han Zhao
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Intrinsic and circuit mechanisms of predictive coding in a grid cell network model

    Inayath Shaikh, Collins Assisi
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Developmental Biology
    2. Neuroscience

    Ptbp1 is not required for retinal neurogenesis and cell fate specification

    Haley Appel, Rogger P Carmen-Orozco ... Seth Blackshaw
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Executive Resources Shape the Impact of Language Predictability Across the Adult Lifespan

    Merle Schuckart, Sandra Martin ... Jonas Obleser
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    An updated catalogue of split-GAL4 driver lines for descending neurons in Drosophila melanogaster

    Jessica L Zung, Shigehiro Namiki ... Gwyneth M Card
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology

    Blue-shifted ancyromonad channelrhodopsins for multiplex optogenetics

    Elena G Govorunova, Oleg A Sineshchekov ... John L Spudich
    Ancyromonad channelrhodopsins advance understanding of ionic selectivity and wavelength regulation in light-gated ion channels, and expand the toolkit for multiplexing with red-shifted fluorescent sensors.
    1. Microbiology and Infectious Disease

    Membrane binding properties of the cytoskeletal protein bactofilin

    Ying Liu, Rajani Karmakar ... Martin Thanbichler
    A combination of cell biological, biochemical, and computational approaches characterizes the conserved membrane-targeting sequence of bactofilins and reveals a mutual influence of membrane binding and bactofilin polymerization.
    1. Cell Biology
    2. Neuroscience

    Maintenance of neuronal TDP-43 expression requires axonal lysosome transport

    Veronica H Ryan, Sydney Lawton ... Michael Emmerson Ward
    Protein, but not mRNA, levels of neurodegenerative disease-associated protein TDP-43 are decreased upon knockdown of BORC, a complex that is required for the anterograde transport of lysosomes.
    1. Neuroscience

    Human single-neuron activity is modulated by intracranial theta burst stimulation of the basolateral amygdala

    Justin M Campbell, Rhiannon L Cowan ... Jon Timothy Willie
    Firing rate analyses revealed neurons throughout the hippocampus, amygdala, orbitofrontal cortex, and anterior cingulate cortex in humans that exhibited heterogeneous responses to intracranial theta burst stimulation of the human brain.
    1. Immunology and Inflammation

    scRNA+TCR-seq Reveals the Proportion and Characteristics of Dual TCR Treg Cells in Mouse Lymphoid and Non-lymphoid Tissues

    Yuanyuan Xu, Qi Peng ... Xinsheng Yao
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Incomplete
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Magazine

    1. Computational and Systems Biology
    2. Genetics and Genomics

    Wnt Signaling: Exploring the origins of a signaling pathway

    Balaji Santhanam
    1. Developmental Biology

    Morphogenesis: Regulating closure of the neural tube in humans

    Leon Qarawani, Jacob H Hanna

  3. Episode 100: September 2025

    1. Neuroscience

    Numerical Cognition: Is ‘number sense’ a sense?

    Toshiya Matsushima
    1. Neuroscience

    Dorsal Vagal Complex: A cell atlas to guide research into appetite control

    Greta Lommi, Thomas A Lutz

  6. Point of View: How the Global South is reshaping scholarly communication

    Humberto Debat, Izuchukwu Azuka Okafor ... Carolina Santacruz-Perez
    1. Neuroscience

    Connectomes: The wiring diagram of an entire animal

    Alex M Winsor, Paul S Katz
  8. See more Magazine articles

Research categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Plant Biology
  17. Stem Cells and Regenerative Medicine
  18. Structural Biology and Molecular Biophysics
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