Developmental Biology

Developmental Biology

eLife reviews research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology

    Imp1 acts as a dosage- and stage-dependent temporal rheostat orchestrating radial glial fate transitions and cortical morphogenesis

    Romie Angelo G Azur, Daniel Feliciano ... Tzumin Lee
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Developmental Biology

    Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels

    Kurt Weir, Pin Lyu ... Seth Blackshaw
    Upregulated expression of transcription factors promoting cone identity in late-stage retinal progenitors drives development of the cone-dominant retina of 13-lined ground squirrels.
    1. Developmental Biology

    Dorsoventral-mediated Shh induction is required for axolotl limb regeneration

    Sakiya Yamamoto, Saya Furukawa ... Akira Satoh
    Dorsoventral contact in axolotl limb blastemas induces Shh, showing how positional identities cooperate to drive the regeneration process.
    1. Developmental Biology
    2. Genetics and Genomics

    Single-cell transcriptomics of X-ray irradiated Drosophila wing discs reveals heterogeneity related to cell-cycle status and cell location

    Joyner Cruz, William Y Sun ... Iswar K Hariharan
    Even in a simple epithelial tissue that is exposed uniformly to X-ray irradiation, cells show marked differences in their transcriptional response based on their location and cell-cycle status.
    1. Developmental Biology

    Jam2 Signaling Functions Downstream of Hand2 To Initiate The Formation Of Organ-Specific Vascular Progenitors In Zebrafish

    Martyna Griciunaite, Julius Martinkus ... Saulius Sumanas
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Developmental Biology

    The Drosophila EGF domain protein uninflatable sets the switch between wrapping glia growth and axon wrapping instructed by Notch

    Marie Baldenius, Steffen Kautzmann ... Christian Klämbt
    In Drosophila larva, the Uninflatable protein helps to switch from FGF-receptor triggered glial growth to Notch triggered wrapping of peripheral axons.
    1. Developmental Biology

    Single-nucleus transcriptional and chromatin accessibility analyses of maturing mouse Achilles tendon uncover the molecular landscape of tendon stem/progenitor cells

    Hiroki Tsutsumi, Tomoki Chiba ... Hiroshi Asahara
    Single-cell profiling reveals CD55+CD248+ tendon stem/progenitor cells.
    1. Developmental Biology

    Genetic Network Shaping Kenyon Cell Identity and Function in Drosophila Mushroom Bodies

    Pei-Chi Chung, Kai-Yuan Ku ... Hung-Hsiang Yu
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Branched actin polymerization drives invasive protrusion formation to promote myoblast fusion during mouse skeletal muscle regeneration

    Yue Lu, Tezin Walji ... Elizabeth H Chen
    Branched actin cytoskeleton is critical for myoblast fusion during mouse skeletal muscle regeneration.
    Version of Record
    Short Report
    • Valuable
    • Convincing
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Massively parallel reporter assay for mapping gene-specific regulatory regions at single nucleotide resolution

    Alastair J Tulloch, Ryan N Delgado ... Constance L Cepko
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
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Highlights

    1. Developmental Biology

    Positional cues and limb regeneration

    Matthew Cherubino, Catherine D McCusker
    1. Developmental Biology

    Special Issue: Reproductive health

    Wei Yan
    1. Developmental Biology
    2. Evolutionary Biology

    Natural History of Model Organisms: E. coqui

    Sarah E Westrick, Mara Laslo, Eva K Fischer

Senior editors

  1. Albert Cardona
    University of Cambridge, United Kingdom
  2. Claude Desplan
    New York University, United States
  3. Jürgen Kleine-Vehn
    University of Freiburg, Germany
  4. See more editors