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    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Pathogen Evolution: Exploring accidental virulence

    Daniel FQ Smith
    Experimentally evolving yeast to adhere better to plastic led to adaptations that increased their ability to cause an infection.
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    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Protein Kinase A: Probing ligand selectivity in pathogens

    Bryan VanSchouwen, Giuseppe Melacini
    Why does protein kinase A respond to purine nucleosides in certain pathogens, but not to the cyclic nucleotides that activate this kinase in most other organisms?
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    1. Developmental Biology

    Development: Investigating the origin of insect metamorphosis

    Xavier Belles
    Experiments exploring the role of juvenile hormone during the life cycle of firebrat insects provide clues about the evolution of metamorphosis.
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    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Stem Cells: Investigating the impact of cannabis

    Merrick Pierson Smela
    The psychoactive component of cannabis, ∆9-THC, affects cell growth and metabolism in early embryonic cell types in mice.
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    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Viruses: Packing up the genome

    Bálint Kiss, Miklós Kellermayer
    Nucleotide and force-dependent mechanisms control how the viral genome of lambda bacteriophage is inserted into capsids.
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    1. Biochemistry and Chemical Biology

    Support Proteins: Getting bacterial cells into shape

    Mrinmayee Bapat, Vani Pande, Pananghat Gayathri
    The conformational state of a structural protein in bacteria can vary, depending on the concentration level of potassium ions or the nucleotide bound to it.
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    1. Computational and Systems Biology

    Genetics: From mouse to human

    Arya Mani
    A deep analysis of multiple genomic datasets reveals which genetic pathways associated with atherosclerosis and coronary artery disease are shared between mice and humans.
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    1. Epidemiology and Global Health

    Sleep: Another benefit of regular sleep

    Tianyi Huang
    A large observational study has found that irregular sleep-wake patterns are associated with a higher risk of overall mortality, and also mortality from cancers and cardiovascular disease.
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    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Transcription: A hub of activity

    Virginia L Pimmett, Mounia Lagha
    Imaging experiments reveal the complex and dynamic nature of the transcriptional hubs associated with Notch signaling.
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    1. Cell Biology

    Trans-Golgi Network: Sorting secretory proteins

    Anup Parchure, Julia von Blume
    A receptor protein called TGN46 has an important role in sorting secretory proteins into vesicles going to different destinations inside cells.
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