Browse our latest Genetics and Genomics articles

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    1. Genetics and Genomics

    Reproducibility of Scientific Claims in Drosophila Immunity: A Retrospective Analysis of 400 Publications

    Hannah Westlake, Fabrice David ... Bruno Lemaitre
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    • Incomplete
    1. Genetics and Genomics

    A retrospective analysis of 400 publications reveals patterns of irreproducibility across an entire life sciences research field

    Joseph Lemaitre, Désirée Popelka ... Bruno Lemaitre
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Genetics and Genomics

    Non-visual light modulates behavioral memory and gene expression in C. elegans

    Zhijian Ji, Bingying Wang ... Dengke K Ma
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Epidemiology and Global Health

    Heterogenous associations of polygenic indices of 35 traits with mortality

    Hannu Lahtinen, Jaakko Kaprio ... Pekka Martikainen
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    A novel high-throughput single-cell DNA sequencing method reveals hidden genomic heterogeneity in the unicellular eukaryote Leishmania

    Gabriel H Negreira, Pieter Monsieurs ... Malgorzata A Domagalska
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Genetics and Genomics

    The RNA-binding protein HuR modulates the expression of the disease-linked CCL2 rs1024611G-rs13900T haplotype

    Feroz Akhtar, Joselin Hernandez Ruiz ... Srinivas Mummidi
    Bioinformatics, RNA-protein interactions, and HuR-based functional studies demonstrated that the rs13900T allele modulates CCL2 transcript levels, providing a functional link between the CCL2 rs1024611G-rs13900T haplotype and disease susceptibility/progression.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Chromosomes: Finding a role for non-coding DNA in trypanosomes

    Markus R Schmidt
    Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.
    Version of Record
    Insight
    1. Genetics and Genomics

    Khdc3 Regulates Metabolism Across Generations in a DNA-Independent Manner

    Liana Senaldi, Nora Hassan ... Matthew Smith-Raska
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics

    The Impact of Stability Considerations on Genetic Fine-mapping

    Alan J Aw, Lionel Chentian Jin ... Yun S Song
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology
    2. Genetics and Genomics

    In situ mutational screening and CRISPR interference reveal that the apterous Early enhancer is required for developmental boundary positioning

    Gustavo Aguilar, Michèle Sickmann ... Martin Müller
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
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