Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Homologous Recombination: Snapshot of an intermediate structure

    Akira Shinohara
    Cryogenic electron microscopy has been used to determine the detailed structure of an intermediate state called a “D-loop” that forms when strands of DNA are exchanged during homologous recombination.
    Version of Record
    Insight
    1. Evolutionary Biology

    Microfossils: Mimicking early life-forms in the lab

    Maarten Lubbers, Dennis Claessen
    Studying the growth of bacteria without cell walls in an artificial environment can shed new light on the proliferation of primitive life-forms billions of years ago.
    Version of Record
    Insight
    1. Cell Biology

    Membrane Biology: Nothing can replace polyunsaturated lipids

    Sofia Rodriguez-Gallardo, Takeshi Harayama
    Genetic studies reveal that polyunsaturated lipids do more than simply increase the fluidity of the cell membrane.
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    Insight
    1. Neuroscience

    Behavioral Neuroscience: The consequences of stress on the brain and fear

    Nicole C Ferrara, Sydney Trask
    A region of the brain called the paraventricular thalamus mediates the impact of stress on unlearned fear responses, but is not involved in learned fear behavior.
    Version of Record
    Insight
    1. Developmental Biology
    2. Neuroscience

    Ribbon Synapses: Taking the tube to the basal pole of hair cells

    Satish R Ghimire, Thomas M Coate
    A stable microtubule network and kinesin motors facilitate the formation of presynaptic ribbons in sensory hair cells in the zebrafish lateral line.
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    Insight
    1. Cell Biology

    Lymphatic System: Closing in on pacemaker cells

    Pin-Ji Lei, Timothy P Padera
    Lymphatic muscle cells orchestrate the contraction of collecting lymphatic vessels in mice.
    Version of Record
    Insight
    1. Plant Biology

    Symbiosis: How plants pick their friends

    Estelle Grundy, Michael Udvardi
    A protein called RIN4 has a central role in helping legumes such as soybean and the bacteria rhizobia to develop a mutually beneficial relationship.
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    Insight
    1. Evolutionary Biology

    Evolutionary Biology: Embracing the complexity of cooperation

    Benjamin Allen
    A theoretical framework for analyzing the evolution of nonlinear cooperative interactions is taking shape.
    Version of Record
    Insight
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Cardiac Repair: Aiming for spatial and temporal control of gene expression

    Stanislao Igor Travisano, Ching-Ling Lien
    Bioluminescent imaging is helping researchers better understand the effectiveness of tissue regeneration enhancers delivered to injured heart tissue by different adeno-associated virus vectors.
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    Insight
    1. Cell Biology

    Senescence: Returning aging cells to productivity

    Rachana S Vaidya, Simon Y Tang
    Platelet-derived growth factors can restore the proliferative potential of senescent cells taken from the degenerated intervertebral discs of aged humans.
    Version of Record
    Insight