Developmental Biology

Developmental Biology

eLife reviews research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology

    Spatiotemporal WNT and BMP gradients orchestrate regional enteroendocrine cell diversity along the Drosophila midgut

    Jiaying Lv, Xingting Guo, Rongwen Xi
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Cell Biology
    2. Developmental Biology

    BICC1 Interacts with PKD1 and PKD2 to Drive Cystogenesis in ADPKD

    Uyen Tran, Andrew J Streets ... Oliver Wessely
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Epigenetic delineation of the earliest cardiac lineage segregation by single-cell multi-omics

    Peng Xie, Xu Jiang ... Chengqi Lin
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Inadequate
    1. Cell Biology
    2. Developmental Biology

    Cross-species insemination reveals mouse sperm ability to enter and cross the fish micropyle

    Suma Garibova, Eva Stickler ... Matteo Avella
    Mouse sperm are unable to bind the zebrafish chorion, yet a subset of hyperactivated sperm can enter and cross the micropyle, suggesting a conserved mechanism of gamete interaction across species.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    HIF1A-mediated pathways promote euploid cell survival in chromosomally mosaic embryos

    Estefania Sanchez-Vasquez, Marianne E Bronner, Magdalena Zernicka-Goetz
    Aneuploid mosaic mouse embryos require hypoxia for survival, and understanding these pathways may inform new strategies to support embryo viability.
    1. Cell Biology
    2. Developmental Biology

    Wnt induces FZD5/8 endocytosis and degradation and the involvement of RSPO-ZNRF3/RNF43 and DVL

    Dong Luo, Jing Zheng ... Xinjun Zhang
    RSPO-ZNRF3/RNF43 specifically regulates the degradation of FZD5/8 under Wnt stimulation independently of DVL.
    1. Developmental Biology
    2. Neuroscience

    Premature vision drives aberrant development of response properties in primary visual cortex

    Sophie V Griswold, Stephen D Van Hooser
    Introducing premature visual experience by opening the closed eyelids early in ferrets caused many cells in the primary visual cortex to mature improperly.
    1. Developmental Biology

    Distinct waves of ovarian follicles contribute to mouse oocyte production

    Qi Yin, Allan C Spradling
    The first follicle wave undergoes atresia to amplify androgen-producing theca cells, while previously unknown wave 1.5 follicles leave quiescence at 2 weeks and produce most of the earliest offspring.
    1. Developmental Biology
    2. Neuroscience

    Neuronal detection triggers systemic digestive shutdown in response to adverse food sources in Caenorhabditis elegans

    Yating Liu, Guojing Tian ... Bin Qi
    A neural-digestive mechanism has been presented for evaluating harmful food.
    1. Developmental Biology

    A tissue boundary orchestrates the segregation of inner ear sensory organs

    Ziqi Chen, Magdalena Żak ... Nicolas Daudet
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
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Highlights

    1. Developmental Biology

    Tracing cell fates in embryos

    Ying Zhang, Qi Chen
    1. Developmental Biology

    Special Issue: Reproductive health

    Wei Yan
    1. Developmental Biology
    2. Evolutionary Biology

    Natural History of Model Organisms: E. coqui

    Sarah E Westrick, Mara Laslo, Eva K Fischer

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Albert Cardona
    University of Cambridge, United Kingdom
  3. Jürgen Kleine-Vehn
    University of Freiburg, Germany
  4. See more editors