Latest research

    1. Medicine

    Navigating the Path: Advice to Physician-Scientists on Choosing a Clinical Specialty

    Talia H Swartz, José E Cavazos ... Christopher S Williams
    Revised
    Reviewed Preprint v2
    Updated
    1. Developmental Biology

    The NTR/prodrug revolution: Tools for controlling cell loss and regeneration

    Gha-Hyun J Kim, Michael Parsons
    Improved nitroreductase variants, optimized prodrugs, and careful experimental design enable scalable, precise cell ablation across model systems for disease modeling, regeneration studies, and high-throughput discovery.
    1. Neuroscience

    Boosting Hyperalignment Performance with Age-specific Templates

    Yuqi Zhang, Maria Ida Gobbini ... Ma Feilong
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Genetics and Genomics

    Autosomal Allelic Inactivation: Variable Replication and Dosage Sensitivity

    Michael B Heskett, Athanasios E Vouzas ... Mathew J Thayer
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Solid
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Enteropathogenic E. coli-mediated Fast and Coordinated Ca2+ responses regulate NF-κB activation

    Fangrui Guo, Roberto Ornelas Guevara ... Guy Tran Van Nhieu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cell Biology
    2. Chromosomes and Gene Expression

    A genetic toolkit for stable episomal transgenesis in the anaerobic gut parasite Blastocystis ST7-B

    M Rey Toleco, Kevin SW Tan, Mark van der Giezen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Ribosomal RNA methylation by GidB modulates discrimination of mischarged tRNA

    Zhuo Bi, Yu-Xiang Chen ... Babak Javid
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Medicine
    2. Structural Biology and Molecular Biophysics

    Direct MRI of collagen

    Jason Daniel Van Schoor, Markus Weiger ... Klaas P Pruessmann
    The direct observation of collagen using magnetic resonance imaging is possible, presenting a new method to study the protein in vivo.
    1. Microbiology and Infectious Disease

    Quantitative RNA pseudouridine landscape reveals dynamic modification patterns and evolutionary conservation across bacterial species

    Letong Xu, Shenghai Shen ... Xin Deng
    Transcriptome-wide profiling of bacterial RNA pseudouridylation maps modification landscapes and nominates candidate regulatory sites, offering a resource and foundation for future mechanistic studies of Ψ function in bacteria.