Highlights

We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Chromosomes and Gene Expression
    2. Medicine

    Gene dosage imbalance disrupts systemic metabolism in the Dp16 Down syndrome mouse model

    Fangluo Chen, Muzna Saqib ... G William Wong
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Psilocin fosters neuroplasticity in iPSC-derived human cortical neurons

    Malin Schmidt, Anne Hoffrichter ... Philipp Koch
    Psilocin induces a durable neuroplastic state in human cortical neurons by enhancing BDNF signaling, neurite complexity, synaptogenesis, and synaptic network activity through 5-HT2A receptor-dependent mechanisms.
    1. Cell Biology
    2. Neuroscience

    Death receptor 6 does not regulate axon degeneration and Schwann cell injury responses during Wallerian degeneration

    Bogdan Beirowski, Haoran Huang, Elisabetta Babetto
    Rigorous analysis in two knockout mouse lines demonstrates that death receptor 6 is not required for axon degeneration or Schwann cell injury responses following peripheral nerve transection.
    Version of Record
    Short Report
    • Valuable
    • Convincing
    1. Immunology and Inflammation

    Nociceptor neurons control pollution-mediated neutrophilic asthma

    Jo-Chiao Wang, Amelia Kulle ... Sebastien Talbot
    Air pollution activates macrophage-derived artemin, sensitizing TRPA1 nociceptors to drive neutrophilic asthma, revealing new therapeutic targets for refractory airway inflammation.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    DNA tensiometer reveals catch-bond detachment kinetics of kinesin-1, -2 and -3

    Crystal R Noell, Tzu-Chen Ma ... William O Hancock
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Convincing
    1. Genetics and Genomics

    A pilot study for whole proteome tagging in C. elegans

    Matthew Eroglu, Oliver Hobert
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Cell Biology
    2. Neuroscience

    Age-dependent H3K9 trimethylation by dSetdb1 impairs mitochondrial UPR leading to degeneration of olfactory neurons and loss of olfactory function in Drosophila

    Francisco Muñoz-Carvajal, Nicole Sanhueza ... Felipe A Court
    1. Biochemistry and Chemical Biology

    In search of nonlipogenic ABCA1 inducers (NLAI): precision coregulator TR-FRET identifies diverse signatures for LXR ligands

    Megan S Laham, Martha Ackerman-Berrier ... Gregory RJ Thatcher
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Computational and Systems Biology

    Fully computational design of PAM-relaxed Staphylococcus aureus Cas9 with expanded targeting capability

    Youcai Xiong, Li-Kuang Tsai ... Xiaoqiang Huang
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Immunology and Inflammation

    Beta-Glucan Modulates Monocyte Plasticity and Differentiation Capacity to Mitigate DSS-Induced Colitis

    Yinyin Lv, Yanyun Fan ... Hongzhi Xu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
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Magazine

    1. Structural Biology and Molecular Biophysics

    Membrane Proteins: A missing link for efflux pumps

    Hilal Wehbi, Isabelle Broutin
    1. Microbiology and Infectious Disease

    Gut Microbiome: Bacteria weigh up costs and benefits of mobile weapons

    Zhao Wang, Yang Fu
    1. Neuroscience

    Neuropathic Pain: Closing in on the causes of chronic neuropathic pain

    Geoffroy Laumet

  4. Point of View: An easy way to improve lab meetings

    Cara Glynn, Tiago Monteiro

  5. Scientific Publishing: Rethinking how research is reviewed and published

    Timothy E Behrens, Yamini Dalal, Diane M Harper
  6. Kangaroo in Broken Hill, Australia

    Episode 102: March 2026

    1. Immunology and Inflammation
    2. Neuroscience

    Microglia: Replacing the immune system of the brain

    Julie Rebejac, Soyon Hong
  8. See more Magazine articles

Categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Physiology
  17. Plant Biology
  18. Stem Cells and Regenerative Medicine
  19. Structural Biology and Molecular Biophysics
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