Highlights

Latest research

    1. Neuroscience

    Dissociable neural substrates of integration and segregation in exogenous attention

    Yujie Chen, Ai-Su Li ... Yang Zhang
    Dissociable neural signatures of integration and segregation provide the first direct neuroimaging evidence for the integration-segregation theory of exogenous attention.
    1. Chromosomes and Gene Expression
    2. Immunology and Inflammation

    The long non-coding RNA Dreg1 is required for optimal ILC2 development

    Sara Quon, Adelynn Tang ... Rhys Allan
    A Gata3 enhancer-embedded long non-coding RNA, Dreg1, was identified as being specifically required for optimal group 2 innate lymphoid cell development.
    1. Neuroscience

    Modeling flexible behavior with remapping-based hippocampal sequence learning

    Yoshiki Ito, Taro Toyoizumi
    A biologically plausible reinforcement learning model that integrates associative memory and hippocampal remapping explains context-dependent flexible behavior, neural dynamics, and psychosis-related symptoms.
    1. Neuroscience

    Characterisation of cold-selective lamina I spinal projection neurons in the mouse

    Aimi N Razlan, Wenhui Ma ... Junichi Hachisuka
    Lamina I projection neurons that respond selectively to skin cooling receive monosynaptic input from Trpm8-expressing primary afferents and innervate brain regions involved in perception of cold and cold defence mechanisms.
    1. Immunology and Inflammation
    2. Neuroscience

    Intravital calcium imaging of meningeal macrophages reveals niche-specific dynamics and aberrant responses to brain hyperexcitability

    Simone Carneiro-Nascimento, Chao Wei ... Dan Levy
    Intravital microscopy of meningeal macrophage Ca²⁺ dynamics reveals previously unknown population heterogeneity, vasomotion-coupled activity, and diverse responses during steady state and neuroinflammatory conditions, offering relevant insights into brain immune regulation.
    1. Neuroscience

    Brainwide dopamine dynamics across sleep-wake transitions

    Changwan Chen, Xun Tu ... Dana Darmohray
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Developmental Biology

    Single-Cell Characterization of Anterior Segment Development: Cell Types, Pathways, and Signals Driving Formation of the Trabecular Meshwork and Schlemm’s Canal

    Revathi Balasubramanian, Nicholas Tolman ... Simon WM John
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cell Biology

    Regulation of sphingolipid synthesis by the C2H2 zinc finger transcription factor Com2 through ubiquitin-proteasome mediated degradation pathway

    Kosei Matsumoto, Ayane Nagai ... Mitsuaki Tabuchi
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Solid
    1. Immunology and Inflammation

    Allosteric disulfide control of ligand binding and endocytosis of the natural killer cell receptor for HLA-G

    Sumati Rajagopalan, Joyce Chiu ... Eric O Long
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid