Highlights
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Closing the neural tube
High-throughput arrayed CRISPR interference screening of organoid models gives insight into genetic regulators of neural tube closure in humans.
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Hippocampal memory
Genetic evidence highlights the roles of atypical protein kinase C isoforms in hippocampal late-phase long-term potentiation and long-term memory.
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Signals for retinal development
Synchronous waves of activity in the developing retina of postnatal mice potentially involve purinergic signalling triggered by apoptotic retinal ganglia.
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Publish-review-curate at eLife
eLife is rethinking how research is reviewed and published.
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Insights into synaptic dysfunction
LRRK2, a protein linked to Parkinson’s disease, interacts with an actin-binding protein, drebrin, to regulate synaptic function and has a role in BDNF-dependent synaptic modulation.
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Science under threat
How should the scientific community respond to ideological attacks on science?
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.
Patrick Allard, UCLA and eLife author
Researchers explain why they published in eLifeMagazine
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