Genetics and Genomics

Genetics and Genomics

eLife reviews research including the genetic basis of health and disease, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. Learn more about what we review and sign up for the latest research.
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Latest articles

    1. Genetics and Genomics
    2. Evolutionary Biology

    The Primate Major Histocompatibility Complex: A Case Study of Gene Family Evolution

    Alyssa Lyn Fortier, Jonathan K Pritchard
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Genetics and Genomics

    MerQuaCo: a computational tool for quality control in image-based spatial transcriptomics

    Naomi Martin, Paul Olsen ... Jack Waters
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Genetics and Genomics

    Independent Validation of Transgenerational Inheritance of Learned Pathogen Avoidance in Caenorhabditis elegans

    Aalimah Akinosho, Joseph Alexander ... Andrés Vidal-Gadea
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Genetics and Genomics

    Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment

    Nicholas Tolman, Taibo Li ... Simon WM John
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Genetics and Genomics

    Ribosomal RNA synthesis by RNA polymerase I is subject to premature termination of transcription

    Chaïma Azouzi, Katrin Schwank ... Christophe Dez
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics

    Chromatin accessibility variation provides insights into missing regulation underlying immune-mediated diseases

    Raehoon Jeong, Martha L Bulyk
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Genetics and Genomics
    2. Neuroscience

    Single-cell transcriptome sequencing for opening the blood-brain barrier through specific mode electroacupuncture stimulation

    Congcong Ma, Zhaoxing Jia ... Xianming Lin
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Neuroscience

    Aging: Unlocking the longevity code with stress

    Loren Cocciolone, Valeria Uvarova, Patricija van Oosten-Hawle
    Manipulating the neuronal pathway responsible for the hypoxic stress response in the worm C. elegans leads to an increase in lifespan.
    Version of Record
    Insight
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Understanding the global rise of artemisinin resistance: Insights from over 100,000 Plasmodium falciparum samples

    Andrew J Balmer, Nina FD White ... Cristina Ariani
    Spatiotemporal analysis of global kelch13 surveillance data reveals that artemisinin resistance is increasing in East Africa, mirroring patterns previously observed in Southeast Asia.
    1. Genetics and Genomics

    Mapping of in vivo cleavage sites uncovers a major role for yeast RNase III in regulating protein-coding genes

    Lee-Ann Notice-Sarpaning, Mathieu Catala ... Ambro van Hoof
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
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Highlights

    1. Genetics and Genomics
    2. Neuroscience

    How stress can extend lifespan

    Loren Cocciolone, Valeria Uvarova, Patricija van Oosten-Hawle
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology
    3. Genetics and Genomics

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Senior editors

  1. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  2. Murim Choi
    Seoul National University College of Medicine, South Korea
  3. Adèle L Marston
    University of Edinburgh, United Kingdom
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