Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Diffusion-weighted magnetic resonance spectroscopy and microstructural modelling longitudinally tracks cell-specific cerebellar development to non-invasively monitor, and better understand, early brain microstructure.
A novel approach has been developed to partition the net biodiversity effect into components associated with positive, negative, and competitive species interactions.
Chronic stress impairs the autoinhibition in locus coeruleus neurons by inducing the internalization of α2A adrenaline receptors, which causes their overexcitation and consequently induces their degeneration by producing active asparagine endopeptidase.
Introducing premature visual experience by opening the closed eyelids early in ferrets caused many cells in the primary visual cortex to mature improperly.
Ana Teresa López-Jiménez, Dominik Brokatzky ... Serge Mostowy
High-content high-resolution microscopy coupled with deep learning-based analysis reveals novel phenotypes at the single-cell level during Shigella infection.
Strong and temporally precise coupling between frontal slow oscillations and fast spindles consistently predicts memory retention across conditions, supporting its role as a fundamental mechanism in sleep-dependent memory consolidation.
Megakaryocytes form a 3D cage of laminin and collagen IV that stabilizes them within their vascular niche, while β1/β3 integrins and MMP are key regulators that assist megakaryocyte maturation and intravasation.
Cecilia Hes, Abigail J Tomlinson ... Paul V Sabatini
The dorsal vagal complex is a highly intricate structure composed of distinct transcriptional classes of glial and neuronal cells, exhibiting many similarities but also notable differences between mice and rats.
The first follicle wave undergoes atresia to amplify androgen-producing theca cells, while previously unknown wave 1.5 follicles leave quiescence at 2 weeks and produce most of the earliest offspring.