Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Functional organoids prepared from chicken embryonic gut consisting of pacemaker cells and smooth muscles undergo periodic contractions, offering a useful tool to understand rhythm control in multicellular systems.
Behavioural patterns among female gorillas indicate that animals guide their aggressive interactions towards more or less powerful groupmates depending on the conditions they experience.
COMMD3 regulates endosomal trafficking outside the Commander holo-complex, revealing that a trafficking complex subunit can function independently of the entire complex.
KLF2 activity and impaired interferon signaling contribute to HIV-1 persistence by restricting antiviral immunity in infected CD4 T cells during early infection.
The substantia nigra inhibits all PPN neurons and causes place aversion, while the globus pallidus selectively inhibits caudal non-cholinergic PPN neurons and causes place preference.
Disrupting full-length BEND2 impairs ovarian reserve establishment without causing male sterility, highlighting a sex-specific role in fertility and offering new insights into genetic contributions to infertility diagnosis and reproductive health.
Bing Guo, Shannon Takala-Harrison, Timothy D O'Connor
hmmIBD outperforms alternative tools in detecting genome segments that are identical-by-descent and uncovering signals of positive selection and demographic history in malaria parasite genomes, underscoring the importance of tool prioritization and optimization for reliable malaria genomic surveillance.
Souleymane Diallo, Kateřina Kašparová ... Robert Hanus
Identification of the trail-following pheromone receptor in the termite Prorhinotermes simplex represents the first functional characterization (deorphanization) of an odorant receptor in termites.
