Immunology and Inflammation

Latest articles

1. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   IFIT1 is rapidly evolving and exhibits disparate antiviral activities across 11 mammalian orders

   Matthew B McDougal, Ian N Boys ... John W Schoggins

   Evolutionary changes in RNA binding and antiviral activity result in diverse IFIT1 functions across mammals, even among closely related species.
2. 1. Immunology and Inflammation

   Resident memory macrophages and trained innate immunity at barrier tissues

   Alisha Kang, Michael D'Agostino ... Zhou Xing

   The increasing knowledge of barrier tissue-resident memory macrophages and trained innate immunity (TII) will help develop both nontarget-specific and target-specific TII-based vaccine strategies.
3. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Glycosylated IgG antibodies accelerated the recovery of haemorrhagic fever with renal syndrome patients

   Chuansong Quan, Lu Wang ... Haifeng Hou
4. 1. Immunology and Inflammation

   Lipopolysaccharide stimulates dynamic changes in B cell metabolism to promote proliferation

   Dana MS Cheung, Momchil Razsolkov ... J Simon C Arthur
5. 1. Immunology and Inflammation

   scRNA+TCR-seq reveals the proportion and characteristics of dual TCR Treg cells in mouse lymphoid and non-lymphoid tissues

   Yuanyuan Xu, Qi Peng ... Xinsheng Yao

   scRNA+TCR-seq technology identifies a high proportion of dual TCR Treg cells in both lymphoid and non-lymphoid tissues of mice, revealing their tissue specificity, TCR repertoire characteristics, and functional phenotypes.
6. 1. Immunology and Inflammation

   Interleukin 10 controls the balance between tolerance, pathogen elimination, and immunopathology in birds

   Dominique Meunier, Ricardo Corona-Torres ... David A Hume

   The impact of IL10 mutation in birds highlights the intrinsic compromise between effective elimination of a pathogen and damage to the host.
7. 1. Immunology and Inflammation

   Metabolic regulation of immune memory and function of microglia

   Nikolaos Nirakis, Sofia Dimothyra ... Vasileia Ismini Alexaki

   Cell metabolic processes, particularly glucose, glutamine, and lipid metabolism, orchestrate inflammatory responses and promote epigenetic changes shaping microglia immune memory.
8. 1. Immunology and Inflammation
   2. Evolutionary Biology

   Evolutionary Adaptations of IRG1 Refines Itaconate Synthesis and Mitigates Innate Immunometabolism Trade-offs

   Richard V Szeligowski, Francois Miros ... Hongying Shen
9. 1. Immunology and Inflammation

   Layers of immunity: Deconstructing the Drosophila effector response

   Faustine Ryckebusch, Yao Tian ... Bruno Lemaitre
10. 1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    The Shigella flexneri effector IpaH1.4 facilitates RNF213 degradation and protects cytosolic bacteria against interferon-induced ubiquitylation

    Luz Saavedra-Sanchez, Mary S Dickinson ... Jörn Coers