Browse our latest Genetics and Genomics articles

Page 6 of 145
    1. Cell Biology
    2. Genetics and Genomics

    Assessment of the histone mark-based epigenomic landscape in human myometrium at term pregnancy

    San Pin Steve Wu, Elvis Quiroz ... Francesco J DeMayo
    Genome-wide epigenetic profiling reveals chromatin regions in the human myometrium involved in functional regulation and hormonal control during pregnancy.
    1. Genetics and Genomics

    Xist RNA binds select autosomal genes and depends on Repeat B to regulate their expression

    Shengze Yao, Yesu Jeon ... Jeannie T Lee
    Xist RNA’s influence extends beyond the X-chromosome and its autosomal influence can be perturbed genetically and pharmacologically.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Upstream open reading frames buffer translational variability during Drosophila evolution and development

    Yuanqiang Sun, Yuange Duan ... Jian Lu
    Upstream open reading frames (uORFs) function as regulatory elements that buffer translation variability, stabilizing protein expression across animal developmental stages and evolutionary timescales.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Deep sequencing of yeast and mouse tRNAs and tRNA fragments using OTTR

    Hans Tobias Gustafsson, Lucas Ferguson ... Oliver J Rando
    A recently developed RNA cloning protocol efficiently captures both intact and fragmented tRNAs.
    1. Genetics and Genomics

    Confirmation of HLA-II associations with TB susceptibility in admixed African samples

    Dayna Adrienne Croock, Yolandi Swart ... Caitlin Uren
    A local-ancestry-aware association model identified a suggestive association peak within the HLA class II region linked to TB in a complex, highly admixed Southern African population.
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Inhibition of mitochondrial protein import and proteostasis by a pro-apoptotic lipid

    Josep Fita-Torró, José Luis Garrido-Huarte ... Markus Proft
    The pro-apoptotic lipid trans-2-hexadecenal impairs mitochondrial protein import and proteostasis by targeting the TOM complex.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Household clustering and seasonal genetic variation of Plasmodium falciparum at the community-level in The Gambia

    Marc-Antoine Guery, Sukai Ceesay ... Antoine Claessens
    Household clustering and seasonal parasite dynamics highlight the need to target asymptomatic carriers for community-based malaria elimination strategies.
    1. Genetics and Genomics

    Mapping of in vivo cleavage sites uncovers a major role for yeast RNase III in regulating protein-coding genes

    Lee-Ann Notice-Sarpaning, Mathieu Catala ... Ambro van Hoof
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics

    Functional analysis across model systems implicates ribosomal proteins in growth and proliferation defects associated with hypoplastic left heart syndrome

    Tanja Nielsen, Anaïs Kervadec ... Alexandre R Colas
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing